Relieving lipid accumulation through UCP1 suppresses the progression of acute kidney injury by promoting the AMPK/ULK1/autophagy pathway

Conclusions: The present findings suggest that lipid accumulation in AKI is directly regulated by UCP1, which can activate cell autophagy and thus significantly inhibit disease progression. It will provide new ideas and targets for the treatment of AKI.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Wei Xiong, Zhiyong Xiong, Anni Song, Chuntao Lei, Chen Ye, Chun Zhang Tags: Research Paper Source Type: research