Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production

Conclusions: Deletion of Aurka in CD19+ B cells led to an increase in IL-6 production, promoting STAT3 activation, which in turn contributed to TPO transcription and megakaryocytopoiesis.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Xin Chen, Chennan Wang, Na Sun, Shuai Pan, Rongqing Li, Xueqin Li, Jie Zhao, Huan Tong, Yangyang Tang, Jing Han, Jianlin Qiao, Hongbin Qiu, Hui Wang, Jing Yang, Takayuki Ikezoe Tags: Research Paper Source Type: research