Candida albicans disorder is associated with gastric carcinogenesis
Conclusions: This study revealed GC-associated mycobiome imbalance characterized by an altered fungal composition and ecology and demonstrated that C. albicans can be a fungal biomarker for GC. With the significant increase of C. albicans in GC, the abundance of Fusicolla acetilerea, Arcopilus aureus, Fusicolla aquaeductuum were increased, while Candida glabrata, Aspergillus montevidensis, Saitozyma podzolica and Penicillium arenicola were obviously decreased. In addition, C. albicans may mediate GC by reducing the diversity and richness of fungi in the stomach, contributing to the pathogenesis of GC.
Source: Theranostics - Category: Molecular Biology Authors: Mengya Zhong, Yubo Xiong, Jiabao Zhao, Zhi Gao, Jingsong Ma, Zhengxin Wu, Yongxi Song, Xuehui Hong Tags: Research Paper Source Type: research
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