Externally triggered smart drug delivery system encapsulating idarubicin shows superior kinetics and enhances tumoral drug uptake and response

Conclusions: We show that a shift in selection of chemotherapeutics is urgently needed, away from the classic drugs towards selection based on properties of a chemotherapeutic in context of the nanoparticle and delivery mode, to maximize the therapeutic efficacy.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Tao Lu, Dieter Haemmerich, Hui Liu, Ann L.B. Seynhaeve, Gerard C. van Rhoon, Adriaan B. Houtsmuller, Timo L.M. ten Hagen Tags: Research Paper Source Type: research