Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells

Conclusion: CMV infection increases the CVD risk of older men by increasing cfPWV. This may be mediated in part by increased proportions of CD4 Tmem, higher numbers of which are found in CMV+ older people and more so among men than women. Given the high prevalence of CMV worldwide, our findings point to a significant global health issue. Novel strategies to mitigate the increased CVD risk associated with CMV may be required.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Frances Kirkham, Alejandra Pera, Amanda M. Simanek, Aalia Bano, George Morrow, Bernhard Reus, Stefano Caserta, Helen E. Smith, Kevin A Davies, Chakravarthi Rajkumar, Florian Kern Tags: Research Paper Source Type: research