MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer

Conclusions: Our results reveal a novel molecular mechanism conferring resistance to ADT and provide a strong rationale for potential therapeutic strategies against CRPC.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Qiji Li, Min Wang, Yanqing Hu, Ensi Zhao, Jun Li, Liangliang Ren, Meng Wang, Yuandong Xu, Qian Liang, Di Zhang, Yingrong Lai, Shaoyu Liu, Xinsheng Peng, Chengming Zhu, Liping Ye Tags: Research Paper Source Type: research