The kynurenine derivative 3-HAA sensitizes hepatocellular carcinoma to sorafenib by upregulating phosphatases

Conclusion: This study demonstrates that 3-HAA sensitizes HCC cells to sorafenib by upregulation of phosphatases, suggesting it as a promising molecule for HCC therapy.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Guifang Gan, Zhaopeng Shi, Chengfang Shangguan, Jieying Zhang, Yuan Yuan, Lei Chen, Weiren Liu, Biao Li, Songshu Meng, Wujun Xiong, Jun Mi Tags: Research Paper Source Type: research