Female mice lacking ER β display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy

Conclusions: Our data provide novel insight into the pathogenesis of female TLE, and indicate ERβ provides a new therapeutic strategy for female TLE patients.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Zhongke Wang, Ruxin Xie, Xiaolin Yang, Huachun Yin, Xin Li, Tianyao Liu, Yuanyuan Ma, Junwei Gao, Zhenle Zang, Ruotong Ruan, Yang Li, Kaixuan Huang, Qingbo Chen, Kaifeng Shen, Shengqing Lv, Chunqing Zhang, Hui Yang, Maragret Warner, Jan-Ake Gustafsson, Sh Tags: Research Paper Source Type: research