KAT6A, a novel regulator of β -catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1

Conclusions: Our findings suggest that the KAT6A/COP1/β-catenin signaling axis plays a critical role in ovarian cancer progression and that targeting the KAT6A/COP1/β-catenin signaling axis could be a novel strategy for treating ovarian cancer.

Source: Theranostics - April 19, 2021 Category: Molecular Biology Authors: Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng Tags: Research Paper Source Type: research