Evaluation of hepatitis B vaccine seroprotection in healthy and polytransfused Egyptian children with β-thalassemia major

Conclusion: Anti-HBs titer wanes with time lapse and became not enough to be immunogenic in a high percentage of thalassemic children especially after the age of 7 years. Recommendations: Booster dose to all multitransfused thalassemic children beyond 2 years of vaccination is recommended. Healthy children aged 7 years or more need booster dose of HBV vaccine to achieve complete immune response.
Source: Egyptian Liver Journal - Category: Gastroenterology Tags: Original articles Source Type: research