Clival chordoma presenting as sphenoid sinus mass.

We present a case of 40 year female with complaint of headache, intermittent vomiting & diminution of vision. CECT Paranasal sinus suggested the possibility of Sphenoid sinus malignancy or metastases was suggested.A functional endoscopy sinus surgery was done and the mass was excised and sent for histopathological examination. Tumor cell were pleomorphic with hyperchromatic nuclei and vacuolated cytoplasm in myxoid background. Immunohistochemically cells were reactive for Cytokeratin, Epithelial membrane antigen. Final diagnosis of Chordoma was made.The purpose of this case report is to add a rare tumor in females to the differential diagnosis of neoplasms of sphenoid sinus and to familiarize otorhinolaryngologists and head and neck surgeons with its pathologic features.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research