Increased in dose to organ at risks did not correlate with the weight loss but did correlate with the lateral neck dimension reduction and volume changes for head and neck patients treated with intensity-modulated radiotherapy.

Conclusion: This study shows the impact of weight loss largely affected the dose deposited to the critical organs when there is a great change in lateral separation and volume changes. Therefore, it is worthwhile to take additional measure in lateral neck separation as a guide in making re-planning decision.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research