Multiple extramedullary plasmacytoma involving the vallecula: A case report with 3-year follow-up.

Discussion: It is difficult to associate multifocal polyps or nodules in the upper airway with EMPs because EMPs have no specific macroscopic appearance or symptom profile. The present case of multifocal EMPs at the larynx and oropharynx is novel, and this is the first case report on vallecular EMP in the related English-language literature. Moreover, this is the first case of multiple EMP that did not progress to multiple myeloma within a 3-year follow-up without adjuvant radiotherapy. Therefore, this case calls into question the need for adjuvant radiotherapy in cases of EMPs if complete excision with negative margins has been performed. However, the patient described herein was still at risk of developing multiple myeloma later in life, hence requiring lifelong follow-up.

Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research