Primary Hodgkin lymphoma: a rare manifestation in the hard palate.

We report one case of 43-year-old white female with an unusualmanifestation extranodal of primary Hodgkin lymphoma in the hard palatewith clinical aspects similar of other infections cutaneous mucosal diseases. Analyses of infectious agents resulted negative. An incisional biopsy  showed lymphoplasmocitary infiltrate with presence of Hodgkin and Reed-Sternberg cells, that  exhibited immunoreactivity for CD30 and Fascin and nonreactivity for CD15, CD45, CD56, CD20, CD3 and TIA1, supporting a diagnosis of classical Hodgkin lymphoma clinical stage according Ann Arbor I-A. The patient was submitted to 3 cycles of chemotherapy (ABVD) and there was no evidence of diseases at 15 moths of follow-up.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research