Temperature-dependent fluorescence of IRDye800CW in imaging of head and neck cancers.

Conclusions: TBR is increased with decreasing sample temperature, suggesting that the clinical exam of fluorescently labeled tissues may be improved at cooler temperatures. Our results indicate that both the rate of signal loss and the change in fluorescence with temperature observed for IRDye800CW are independent of the conjugating antibody.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research