CXCR4 antagonist inhibits perineural invasion of adenoid cystic carcinoma.

Conclusions CXCR4 is highly expressed in ACC and is associated with perineural invasion. AMD3100, which can effectively diminish perineural invasion of ACC in vitro and in vivo, may have an adjuvant role in the management of ACC.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research