The diagnostic value of methylated DNA in laryngeal squamous cell carcinoma: meta-analysis.

Conclusion In view of the property that aberrant DNA methylation occurs in the early developmental stages of LSCC, methylation markers aregood for the detection of visually undetectable cases in the LSCCtissues. However, based on the current markers panel, the accuracy of methylated DNA markers are not satisfactory for clinical use. Identification of novel methylated markers with higher sensitivity and specificity is warranted.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research