Upile T, Jerjes W, Singh S, Al-Khawalde M, Hamdoon Z, Radhi H, Hopper C. The use of specific anti-growth factor antibodies to abrogate the oncological consequences of transfusion in head & neck squamous cell carcinoma: An in vitro study. Head Neck Oncol. 2012 May 16;4(1):22.

Conclusion Perioperative blood transfusion is associated with reduced prognosis in a number of solid malignancies including HNSCC. However this phenomenon is abrogated by the use of anti-endothelial growth factor antibodies. This suggests that the original effect was mediated by the endothelial growth factor family.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research