Eckardt AM, Rana M, Essig H, Gellrich NC. Orbital metastases as first sign of metastatic spread in breast cancer: case report and review of the literature. Head Neck Oncol. 2011 Aug 22;3:37.

Conclusion In patients with a previous history of breast cancer who complain even of mild ophthalmologic symptoms such as local pain, periorbital edema, it is important to consider ocular or orbital metastatic disease. Adequate 3D-Imaging followed by a biopsy will usually confirm the diagnosis.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research