Bohannon IA, Carroll WR, Magnuson JS, Rosenthal EL. Closure of post-laryngectomy pharyngocutaneous fistulae. Head Neck Oncol. 2011 May 26;3:29.

Conclusions Delayed secondary repair of pharygocutaneous fistulas after salvage laryngectomy is associated with a higher complication rate and poor success rates compared to use of vascularized tissue at the time of salvage laryngectomy. Prolonged wound healing in these patients is associated with hypothyroidism.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research