Association of TNFAIP3 and TNFRSF1A variation with multiple sclerosis in a German case–control cohort

In conclusion, evidence is accumulating that polymorphisms in both TNFAIP3 and TNFRSF1A genes play a role in MS pathogenesis. Additional studies are warranted to further elucidate the role of TNF pathway variation for MS development.

Source: International Journal of Immunogenetics - February 12, 2015 Category: Genetics & Stem Cells Authors: S. Hoffjan, A. Okur, J. T. Epplen, S. Wieczorek, A. Chan, D. A. Akkad Tags: Original Article Source Type: research