Mechanism of succinate efflux upon reperfusion of the ischaemic heart

Conclusion  Succinate release upon reperfusion of the ischaemic heart is mediated by MCT1 and is facilitated by the acidification of the myocardium during ischaemia. These findings will allow the signalling interaction between succinate released from reperfused ischaemic myocardium and SUCNR1 to be explored.
Source: Cardiovascular Research - Category: Cardiology Source Type: research