Examination of the Effects of Thiamine and Thiamine Pyrophosphate on Doxorubicin-Induced Experimental Cardiotoxicity

Conclusion and Implications: The cardiotoxic effect of doxorubicin originated from the inhibition of TPK enzyme resulting in insufficient production of thiamine pyrophosphate.

http://cpt.sagepub.com/cgi/content/abstract/20/2/221?rss=1

Source: Journal of Cardiovascular Pharmacology and Therapeutics - February 9, 2015 Category: Cardiology Authors: Polat, B., Suleyman, H., Sener, E., Akcay, F. Tags: Experimental Studies Source Type: research