Potential Pitfalls in Interpretation of PET/CT Findings in the Thorax

18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) is widely used in current clinical practice. The majority of PET/CT applications in the thorax involve the evaluation of solitary pulmonary nodules for malignancy, staging and restaging of oncologic patients, assessment of treatment response following therapy, and identification of residual or recurrent disease. These functions reflect the fact that cancer cells demonstrate increased uptake of glucose and glucose analogues such as FDG, as well as an increased rate of glycolysis.

Source: Seminars in Roentgenology - February 7, 2015 Category: Radiology Authors: Brett W. Carter, Sonia L. Betancourt, Chitra Viswanathan, Osama Mawlawi, Edith M. Marom, Mylene T. Truong Source Type: research