STABIL-study: The Course of Therapy, Safety and Pharmacokinetic Parameters of Conversion of Prograf ® to Tacrolimus HEXAL®/Crilomus® in Renal Transplant Recipients - an Observational Study in Germany

CONCLUSION: In conclusion, conversion to the generic tacrolimus formulation can be considered safe and feasible in long-term kidney transplant recipients in Germany. As suggested by guidelines, a vigilant therapeutic drug monitoring is recommended to account for possible tacrolimus concentration variability on the individual patient level.PMID:33588739 | DOI:10.2174/1574884716666210215102756

Source: Current Clinical Pharmacology - February 16, 2021 Category: Drugs & Pharmacology Authors: Lukas J Lehner Klaus Kalb Karl Weigand Ulrich Pein Peter Schenker Wolfgang Seeger Robert Roehle Kerstin Dienes Fabian Halleck Klemens Budde Source Type: research