Ex vivo Ikk β ablation rescues the immunopotency of mesenchymal stromal cells from diabetics with advanced atherosclerosis

ConclusionsConstitutively active IKK β reduces the immunopotency of atherosclerosis+T2DM MSC by changing their secretome composition. Modulation of IKKβ in atherosclerosis+T2DM MSCs enhances their myocardial repair ability.

Source: Cardiovascular Research - July 1, 2020 Category: Cardiology Source Type: research