STABIL-study: The Course of Therapy, Safety and Pharmacokinetic Parameters of Conversion of Prograf ® to Tacrolimus HEXAL®/Crilomus® in Renal Transplant Recipients - an Observational Study in Germany.

CONCLUSION: In conclusion, conversion to the generic tacrolimus formulation can be considered safe and feasible in long-term kidney transplant recipients in Germany. As suggested by guidelines, a vigilant therapeutic drug monitoring is recommended to account for possible tacrolimus concentration variability on the individual patient level.
PMID: 33588739 [PubMed - as supplied by publisher]

Source: Current Clinical Pharmacology - February 14, 2021 Category: Drugs & Pharmacology Authors: Lehner LJ, Kalb K, Weigand K, Pein U, Schenker P, Seeger W, Roehle R, Dienes K, Halleck F, Budde K Tags: Curr Clin Pharmacol Source Type: research