Generation of dyskeratosis congenita-like hematopoietic stem cells through the stable inhibition of DKC1

Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marr...

Source: Stem Cell Research and Therapy - January 29, 2021 Category: Stem Cells Authors: Carlos Carrascoso-Rubio, Hidde A. Zittersteijn, Laura Pintado-Berninches, Beatriz Fern ández-Varas, M. Luz Lozano, Cristina Manguan-Garcia, Leandro Sastre, Juan A. Bueren, Rosario Perona and Guillermo Guenechea Tags: Short report Source Type: research