Where and when should natural killer cells be tested in women with repeated implantation failure?

Despite the new technologies, human implantation remains a barrier in assisted reproduction (Edwards, 2007). At the time of implantation, there seems to be a dialog between the embryo and the endometrium (Roberts et al., 2008). In this dialog, the main role is played by the embryo (Dior et al., 2014). Embryos resulting from sperm and egg donation or those chromosomally normal after preimplantation genetic diagnosis (PGD) are usually considered to be of very good quality (Capalbo et al., 2014). However, sometimes, even after transferring very good quality embryos, pregnancy is not achieved.

Source: Journal of Reproductive Immunology - February 4, 2015 Category: Allergy & Immunology Authors: Isabel Santillán, Ignacio Lozano, Julia Illán, Victoria Verdú, Santiago Coca, Jose Manuel Bajo-Arenas, Felipe Martinez Source Type: research