Nogo-B receptor is required for stabilizing TGF- β type I receptor and promotes the TGF- β 1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer

Conclusions: Our findings provide a novel role of NgBR in modulating TGF-β1-induced EMT and propose NgBR as a new therapeutic target for treating NSCLC patients.

Source: Journal of Cancer - January 15, 2021 Category: Cancer & Oncology Authors: Donghua Wu, Baofeng Zhao, Yang Song, Xinming Chi, Hailu Fu, Tiantong Guan, Liyuan Zhang, Xueguang Yang, Ke Hu, Rong Huang, Xiaomeng Jin, Qing Robert Miao, Shujuan Shao Tags: Research Paper Source Type: research