Upregulation of miR-1254 promotes Hepatocellular Carcinoma Cell Proliferation, Migration, and Invasion via Inactivation of the Hippo-YAP signaling pathway by decreasing PAX5

In conclusion, miR-1254 promoted proliferation, migration, and invasion of HCC cells via decreasing Hippo signaling through targeting PAX5 in vitro and in vivo. This miRNA might be a therapeutic target for HCC.

Source: Journal of Cancer - January 15, 2021 Category: Cancer & Oncology Authors: Xu Lu, Chao Yang, Yuanchang Hu, Jian Xu, Chengyu Shi, Jianhua Rao, Weixin Yu, Feng Cheng Tags: Research Paper Source Type: research