PET imaging facilitates antibody screening for synergistic radioimmunotherapy with a 177Lu-labeled α PD-L1 antibody

Conclusions: PET imaging of 89Zr-labeled antibodies is an effective method for antibody screening. RIT with a 177Lu-labeled αPD-L1 antibody could successfully upregulate antitumor immunity in the tumor microenvironment and turn “cold” tumors “hot” for immunotherapy.

Source: Theranostics - January 15, 2021 Category: Molecular Biology Authors: Jingyun Ren, Mengxin Xu, Junyi Chen, Jie Ding, Peipei Wang, Li Huo, Fang Li, Zhibo Liu Tags: Research Paper Source Type: research