Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice

Conclusions: Platr4 functions to inactivate Nlrp3 inflammasome via intercepting NF-κB signaling. This lncRNA might be an attractive target that can be modulated to ameliorate the pathological conditions of steatohepatitis.

Source: Theranostics - January 15, 2021 Category: Molecular Biology Authors: Yanke Lin, Shuai Wang, Lu Gao, Ziyue Zhou, Zemin Yang, Jingpan Lin, Shujing Ren, Huijie Xing, Baojian Wu Tags: Research Paper Source Type: research