Brain-derived neurotrophic factor precursor in the immune system is a novel target for treating multiple sclerosis

Conclusion: The findings suggest that proBDNF from immune cells promotes the immunopathogenesis of MS. Monoclonal Ab-proB may be a promising therapeutic agent for treating MS.

Source: Theranostics - January 15, 2021 Category: Molecular Biology Authors: Zhao-Lan Hu, Cong Luo, Plinio Reinaldo Hurtado, Hui Li, Shuang Wang, Bo Hu, Jun-Mei Xu, Yang Liu, Shi-Qing Feng, Ernesto Hurtado-Perez, Kang Chen, Xin-Fu Zhou, Chang-Qi Li, Ru-Ping Dai Tags: Research Paper Source Type: research