Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice

Conclusions: These results suggest that NLN and NEW are promising metastasis-inhibiting peptide therapeutics and targeting moieties for CD44v6-expressing metastases.

Source: Theranostics - January 15, 2021 Category: Molecular Biology Authors: Fatima Khan, Smriti Gurung, Gowri Rangaswamy Gunassekaran, Sri Murugan Poongkavithai Vadevoo, Lianhua Chi, Uttapol Permpoon, Md. Enamul Haque, Yun-Ki Lee, Soo-Woong Lee, Soyoun Kim, Byungheon Lee Tags: Research Paper Source Type: research