Exome Array Analysis Identifies CAV1/CAV2 as a Susceptibility Locus for Intraocular Pressure [Glaucoma]
Conclusions.
Our results suggest that novel genetic variants and genes with multiple, less common variants may play a role in the control of IOP. The implication of the caveolin genes, CAV1/CAV2, as a common genetic factor influencing both IOP variations and POAG may provide new insights of the underlying mechanism leading to glaucoma and glaucomatous visual field loss.
Source: Investigative Ophthalmology - Category: Opthalmology Authors: Chen, F., Klein, A. P., Klein, B. E. K., Lee, K. E., Truitt, B., Klein, R., Iyengar, S. K., Duggal, P. Tags: Glaucoma Source Type: research