The Effect of TIMP-1 on the Cone Mosaic in the Retina of the Rat Model of Retinitis Pigmentosa [Anatomy and Pathology/Oncology]
Conclusions.
These findings confirm that TIMP-1 induced M-cone mosaics in S334ter-line-3 to gain homogeneity without reaching the degree of regularity seen in normal retinal mosaics. Even if TIMP-1 fails to promote regularity, the effects of this drug on homogeneity appear to be so dramatic that TIMP-1 may be a potential therapeutic agent. TIMP-1 improves sampling of the visual field simply by causing homogeneity.
Source: Investigative Ophthalmology - Category: Opthalmology Authors: Ji, Y., Yu, W.-Q., Eom, Y. S., Bruce, F., Craft, C. M., Grzywacz, N. M., Lee, E.-J. Tags: Anatomy and Pathology/Oncology Source Type: research
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