Role of C/EBP Homologous Protein in Retinal Ganglion Cell Death After Ischemia/Reperfusion Injury [Retina]

Conclusions.
Absence of CHOP partially protects against RGC loss and reduction in retinal function after I/R injury, indicating that CHOP and, thus, ER stress play an important role in RGC apoptosis in retinal I/R injury.

Source: Investigative Ophthalmology - January 2, 2015 Category: Opthalmology Authors: Nashine, S., Liu, Y., Kim, B.-J., Clark, A. F., Pang, I.-H. Tags: Retina Source Type: research