Pioglitazone Restores IGFBP-3 Levels Through DNA PK in Retinal Endothelial Cells Cultured in Hyperglycemic Conditions [Retinal Cell Biology]

Conclusions. Our findings suggest that pioglitazone mediates regulation of IGFBP-3 via activation of PKA/DNA PK pathway in hyperglycemic retinal endothelial cells.

http://www.iovs.org/cgi/content/full/56/1/177?rss=1

Source: Investigative Ophthalmology - January 13, 2015 Category: Opthalmology Authors: Thakran, S., Zhang, Q., Morales-Tirado, V., Steinle, J. J. Tags: Retinal Cell Biology Source Type: research