Cone Responses in Usher Syndrome Types 1 and 2 by Microvolt Electroretinography [Retina]

Conclusions.
Cycle-by-cycle ERG showed progressive loss of amplitude in both USH1 and USH2 subjects, comparable to that reported with psychophysical measures. Usher subjects showed abnormal ERG response latency, but this changed less than amplitude with time. In USH syndrome, CxC ERG is more sensitive than conventional ERG and warrants consideration as an outcome measure in USH treatment trials.

Source: Investigative Ophthalmology - January 6, 2015 Category: Opthalmology Authors: Zein, W. M., Falsini, B., Tsilou, E. T., Turriff, A. E., Schultz, J. M., Friedman, T. B., Brewer, C. C., Zalewski, C. K., King, K. A., Muskett, J. A., Rehman, A. U., Morell, R. J., Griffith, A. J., Sieving, P. A. Tags: Retina Source Type: research