Loss of Citron Kinase Affects a Subset of Progenitor Cells That Alters Late but Not Early Neurogenesis in the Developing Rat Retina [Retinal Cell Biology]

Conclusions. Our study showed that CitK is not required for a subset of RPCs before E14, but is necessary for RPC survival post E14. This in turn results in normal early embryonic neurogenesis, but severely compromised later embryonic and postnatal neurogenesis.

http://www.iovs.org/cgi/content/full/56/2/787?rss=1

Source: Investigative Ophthalmology - February 2, 2015 Category: Opthalmology Authors: Karunakaran, D. K. P., Chhaya, N., Lemoine, C., Congdon, S., Black, A., Kanadia, R. Tags: Retinal Cell Biology Source Type: research