Annurca Apple Biophenols’ Effects in Combination with Cisplatin on A549 Cells

Conclusion: In conclusion, the co-administration of AFPE with CDDP does not interfere with its chemotherapy efficacy. Therefore, Annurca apple could be a good candidate to act as an antioxidant and potentially reduce the side effects of CDDP therapy, although the joint effect of AFPE and CDDP on normal cells is still unclear. More studies will be needed to analyze the molecular mechanism of AFPE and in vivo studies will also be needed to verify the anticancer effects. These findings may represent a starting point for the design of new clinical trials for use in cancer treatment.
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research