Withdrawal: Exercise increases mitochondrial PGC-1{alpha} content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. [Withdrawals/Retractions]

This article has been withdrawn by the authors. In Fig. 6B the top two panels, corresponding to TOMM22 and Bcl-2, with trypsin treatment samples presented background issues. In Fig. 5, the H2B and VDAC immunoblot panels were duplicated and flipped vertically. The immunoblots for VDAC in Fig. 7A and the VDAC panels in Fig. 8B were duplicated and represented different experimental conditions. The immunoblots for Tfam (IP: PGC-1a) in Fig. 7A and the nuclear PGC-1a in Fig. 5 were flipped vertically. The immunoblots for PGC-1a (IP: Tfam) in Fig. 7B and PGC-1a (Input: D-Loop) in Fig. 8 were flipped horizontally and duplicated. Due to the lack of original data, the authors wish to withdraw this article.

Source: Journal of Biological Chemistry - December 18, 2020 Category: Chemistry Authors: Adeel Safdar, Jonathan P. Little, Andrew J. Stokl, Bart P. Hettinga, Mahmood Akhtar, Mark A. Tarnopolsky Tags: Withdrawals/Retractions Source Type: research