Information transfer by exosomes: a new frontier in hematologic malignancies

Exosomes are small (30–150mm) vesicles secreted by all cell types and present in all body fluids. They are emerging as vehicles for delivery of membrane-tethered signaling molecules and membrane enclosed genes to target cells. Exosome-mediated information transfer allows for crosstalk of cells within the hematopoietic system and for interactions between hematopoietic cells and local or distant tissue cells. Exosomes carry physiological signals essential for health and participate in pathological processes, including malignant transformation.
Source: Blood Reviews - Category: Hematology Authors: Tags: Review Source Type: research