[Research Articles] Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1

This study reports the identification and validation of a direct HSF1 inhibitor and provides a path for the development of a small-molecule HSF1-targeted therapy for prostate cancers and other therapy-resistant cancers.

Source: Science Translational Medicine - December 16, 2020 Category: Biomedical Science Authors: Dong, B., Jaeger, A. M., Hughes, P. F., Loiselle, D. R., Hauck, J. S., Fu, Y., Haystead, T. A., Huang, J., Thiele, D. J. Tags: Research Articles Source Type: research