A Randomized, Double-Blind Pilot Study of Dexmedetomidine Versus Midazolam for Intensive Care Unit Sedation: Patient Recall of Their Experiences and Short-Term Psychological Outcomes

Conclusions: Transitioning benzodiazepine sedation to dexmedetomidine when patients qualify for daily awakenings may reduce the development of delirium and facilitate remembrance of ICU experiences but may lead to manifestations of ASD. Monitoring hypotension is required for both the sedatives. Additional comparative studies focusing on the long-term impact of ICU recall and psychological outcomes are needed.

http://jic.sagepub.com/cgi/content/abstract/30/3/167?rss=1

Source: Journal of Intensive Care Medicine - January 30, 2015 Category: Intensive Care Authors: MacLaren, R., Preslaski, C. R., Mueller, S. W., Kiser, T. H., Fish, D. N., Lavelle, J. C., Malkoski, S. P. Tags: Original Research Source Type: research