Computationally modeling mammalian succinate dehydrogenase kinetics identifies the origins and primary determinants of ROS production [Bioenergetics]

In this study, we showed the importance of analyzing enzyme kinetics and associated side reactions in a consistent, quantitative, and biophysically detailed manner using a diverse set of experimental data to interpret and explain experimental observations from a unified perspective.

Source: Journal of Biological Chemistry - November 6, 2020 Category: Chemistry Authors: Neeraj Manhas, Quynh V. Duong, Pilhwa Lee, Joshua D. Richardson, John D. Robertson, Michael A. Moxley, Jason N. Bazil Tags: Computational Biology Source Type: research