Correlation Between the Metabolic Conversion of a Capecitabine Metabolite, 5-Deoxy-5-fluorocytidine, and Creatinine Clearance

Conclusion: Metabolism of 5’-DFCR to form 5’-DFUR increased as CLcr decreased but the mechanism remains unknown.

Source: In Vivo - November 3, 2020 Category: Research Authors: INAISHI, T., FUJITA, K.-I., MATSUMOTO, N., SHIMOKATA, T., MAEDA, O., KIKUMORI, T., HATTORI, N., NAKAYAMA, G., ANDO, Y. Tags: Clinical Studies Source Type: research