The KDR (VEGFR-2) Genetic Polymorphism Q472H and c-KIT Polymorphism M541L Are Associated With More Aggressive Behaviour in Astrocytic Gliomas

Conclusion: This study highlights the role of single-nucleotide variants (SNVs) that may be considered non-pathogenic and suggests the prognostic significance for survival of KIT rs3822214 and KDR rs1870377 and potential importance in planning new treatment strategies for gliomas.

Source: Cancer Genomics and Proteomics - October 24, 2020 Category: Cancer & Oncology Authors: ZAMAN, N., DASS, S. S., DU PARCQ, P., MACMAHON, S., GALLAGHER, L., THOMPSON, L., KHORASHAD, J. S., LIMBACK-STANIC, C. Tags: Experimental Studies Source Type: research