A computer-simulated mechanism of familial Alzheimer’s disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase

Publication date: Available online 21 October 2020Source: Journal of Structural BiologyAuthor(s): Budheswar Dehury, Arun K. Somavarupu, Kasper P. Kepp

Source: Journal of Structural Biology - October 22, 2020 Category: Biology Source Type: research